Diagnostic Technologies

Our group has developed a portable, battery-operated, high-resolution microendoscope (HRME) that provides subcellular images of the epithelium, delineating the cellular and morphologic changes associated with cancer. HRME can be inserted into a body cavity, such as the mouth, esophagus, or cervix. To visualize cells, a non-toxic fluorescent dye that stains cell nuclei is applied to the suspicious area and the HRME is inserted into the body. Within seconds of applying the dye and inserting the HRME, a magnified image of the cells is displayed on the camera’s LCD screen in real-time.

Hemospec is a portable, low-cost device that accurately and safely assesses hemoglobin concentration. This technology will provide healthcare workers in low-resource settings with the information necessary to diagnose anemia. Current point-of-care devices are inaccurate, time-consuming, or require operating costs that are too high for clinics in low-resource areas.

In order to help health care workers in low resource settings take in-focus, color-accurate photos of skin lesions, Rice 360° has developed a cell-phone attachment. This device consists of the phone attachment part, as well as a removable arm with a 2cm ruler and color scale. This teledermatology phone attachment system will allow nurses to take in-focus pictures of skin lesions from a distance of 10 cm away. Testing shows that the 10 cm distance provides in focus and accurately colored pictures 100% of the time. In contrast, the 7cm distance was more variable and only provided in focus pictures a few times throughout testing.

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